Bridging verbal coordination and neural dynamics

Auteurs

Schwab-Mohamed I, Mercier MR, Trebuchon A, Morillon B, Lancia L, Schön D

Les auteurs en lien sont membres de l'INS.

Équipes

D-CAP

Résumé

Our use of language, which is profoundly social in nature, essentially takes place in interactive contexts and is shaped by precise coordination dynamics that interlocutors must observe. Thus, language interaction is highly demanding on fast adjustment of speech production. Here, we developed a real-time coupled-oscillators virtual partner (VP) that allows – by changing the coupling strength parameters – to modulate the ability to synchronise speech with a virtual speaker. Then, we recorded the intracranial brain activity of 16 patients with drug-resistant epilepsy while they performed a verbal coordination task with the VP. More precisely, patients had to repeat short sentences synchronously with the VP. This synchronous speech task is efficient to highlight both the dorsal and ventral language pathways. Importantly, combining time-resolved verbal coordination and neural activity shows more spatially differentiated patterns and different types of neural sensitivity along the dorsal pathway. More precisely, high-frequency activity (HFa) in left secondary auditory regions is highly sensitive to verbal coordinative dynamics, while primary regions are not. Finally, while bilateral eng

Our use of language, which is profoundly social in nature, essentially takes place in interactive contexts and is shaped by precise coordination dynamics that interlocutors must observe. Thus, language interaction is highly demanding on fast adjustment of speech production. Here, we developed a real-time coupled-oscillators virtual partner (VP) that allows – by changing the coupling strength parameters – to modulate the ability to synchronise speech with a virtual speaker. Then, we recorded the intracranial brain activity of 16 patients with drug-resistant epilepsy while they performed a verbal coordination task with the VP. More precisely, patients had to repeat short sentences synchronously with the VP. This synchronous speech task is efficient to highlight both the dorsal and ventral language pathways. Importantly, combining time-resolved verbal coordination and neural activity shows more spatially differentiated patterns and different types of neural sensitivity along the dorsal pathway. More precisely, high-frequency activity (HFa) in left secondary auditory regions is highly sensitive to verbal coordinative dynamics, while primary regions are not. Finally, while bilateral eng

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