À propos
PhysioNet - Team Lead
Phone: +33 4 91 32 42 49
Christophe Bernard’s main interest is to understand the mechanisms underlying the construction of an epileptic brain as well as the mechanisms underlying seizure genesis and propagation, focusing on Temporal Lobe Epilepsy (TLE). These research themes are being addressed using a wide array of disciplines, including electron microscopy, morphology, immunohistochemistry, in vitro and in vivo electrophysiology, behavior, mathematics and modeling. When the techniques were not available within the group (e.g. molecular biology), external collaborations have been developed. More recently, we started to design the tools necessary for some of our research programs. For example, we designed a recording device based on organic transistors, which outperforms any other recording device for field potential measurements. We also developed The Virtual Mouse Brain platform. Over the years, using experimental models of TLE, our group has developed a solid international reputation in the field of epilepsy.
Christophe Bernard was awarded the Michael Prize for epilepsy in 2007 and the Felix Innovation Prize in 2013 for the organic transistor. He isinvited to give between 5 and 15 lectures/keynotes every year. He is Editor in Chief of eNeuro, the open access Neuroscience journal of the Society for Neuroscience (SfN) and past reviewing editor for Science and Journal of Neuroscience.
Publications
- Timing is everything: Expert opinion on researching epilepsy rhythms by the ILAE Task Force on Chronobiology — Epilepsia, 2026
- Dorso‐Ventral and Night‐Day Regulation of Extracellular K <sup>+</sup> Dynamics in Mouse Hippocampal Astrocytes — Glia, 2026
- Chronoepileptology: Mapping the Rhythms of Seizure Risk — Epilepsy Currents, 2025
- Flexible Depth Probes with PEDOT:PSS Microelectrodes for Chronic Recording and Stimulation — ACS Applied Materials & Interfaces, 2025
- Diurnal dynamics of the Zbtb14 protein in the ventral hippocampus are disrupted in epileptic mice — Neuroscience, 2025
- Astrocytes and Potassium Homeostasis in the Central Nervous System in Physiology and Epilepsy — Glial Engineering and Glial Interfaces, 2025
- A mechanism for the emergence of low-dimensional structures in brain dynamics — npj Systems Biology and Applications, 2025
- Multiscale co-simulation design pattern for neuroscience applications — Frontiers in Neuroinformatics, 2024
- Hippocampal ripples coincide with “up-state” and spindles in retrosplenial cortex — Cerebral Cortex, 2024
- A Classification of Seizures Based on Dynamics — Jasper's Basic Mechanisms of the Epilepsies, 2024
- Perturbed Information Processing Complexity in Experimental Epilepsy — The Journal of Neuroscience, 2023
- Interictal Spike and Loss of Hippocampal Theta Rhythm Recorded by Deep Brain Electrodes during Epileptogenesis — Sensors, 2022
- The nucleus reuniens controls long-range hippocampo-prefrontal gamma synchronization during slow oscillations — Journal of Neuroscience, 2018
- The Virtual Epileptic Patient: Individualized whole-brain models of epilepsy spread — NeuroImage, 2017
